Many medicinal plants claimed traditionally for its properties to cure the diseases. Some of them also claim the property to control the diabetic condition in humans but systematic evaluation of many plants are not done yet. Echinops echinatus Roxb, (Compositae) (EE), commonly known as brahmadandi, possesses several medicinal properties; little is known about its traditional use as antidiabetic. The purpose of the study was to evaluate the antidiabetic activity of methanol extract of roots bark (RBEE) (250 and 350 mg/kg) and aerial parts (APEE) (250 and 350 mg/kg) of Echinops echinatus using alloxan induced hyperglycemia. In the same study the action of the extract on diabetes induces hyperlipidemia was analysed where the extracts significantly lowered the elevated cholesterol as well as LDL level. The antihyperglycemic action of the extracts may be due to the blocking of glucose absorption. All extract of Echinops ehinatus produced a significant antidiabetic activity.
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